Cetirizine USP RC B

Cetirizine USP RC B - Names and Identifiers

Name	4-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
Synonyms	Cetirizine USP RC B Cetirizine Impurity 46 Cetirizine Related CoMpound Cetirizine Impurity 19 DiHCl 2-(4-benzhydryl-piperazino)-ethanol 2-(4-Benzhydrylpiperazin-1-yl)ethanol dihydrochloride 4-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL DIHYDROCHLORIDE 2-(4-benhdryl-piperazin-1-yl)-enthanol dihydrochloride 1-diphenylmethyl-4-(2-hydroxyethyl) piperazine dihydrochloride 1-diphenylMethyl-4-(2-hydroxyethyl) piperazine dihydrochloride
CAS	108983-83-1
EINECS	1533716-785-6
InChI	InChI=1/C19H24N2O.2ClH/c22-16-15-20-11-13-21(14-12-20)19(17-7-3-1-4-8-17)18-9-5-2-6-10-18;;/h1-10,19,22H,11-16H2;2*1H

Cetirizine USP RC B - Physico-chemical Properties

Molecular Formula	C19H26Cl2N2O
Molar Mass	369.33
Storage Condition	2-8°C

Cetirizine USP RC B - Risk and Safety

HS Code

2933599550

Cetirizine USP RC B - Introduction

1-Benzhydryl-4-(2-hydroxyethyl) piperazine dihydrochloride is an organic compound with the chemical formula C'4o H₂ N₂ O₂ 2HCl. It is a white crystalline powder, soluble in water. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in water and alcohol.
-Molecular weight: about 408.39g/mol.
-Melting point: about (thermal analysis) 227-231°C.

Use:
1-benzhydryl-4-(2-hydroxyethyl) piperazine dihydrochloride is a broad-spectrum antimicrobial agent commonly used to treat respiratory infections, urinary tract infections and skin infections. It can also be used as a reagent in biochemical research.

Preparation Method:
The preparation method of 1-benzhydryl-4-(2-hydroxyethyl) piperazine dihydrochloride can be achieved by the following steps:
1. Dissolve 1-benzhydryl-4-(2-hydroxyethyl) piperazine in dichloromethane.
2. hydrochloric acid is added to react to generate 1-diphenylmethyl -4-(2-hydroxyethyl) piperazine dihydrochloride.
3. The solid product was filtered and washed with cold ether.
4. After the crystals were isolated and dried, the pure product was obtained.

Safety Information:
The use and operation of 1-benzhydryl-4-(2-hydroxyethyl) piperazine dihydrochloride should follow the following safety measures:
-The substance is irritating and direct contact with skin and eyes should be avoided.
-Use protective gloves, goggles and protective masks during operation.
-Avoid inhaling dust and keep the workplace well ventilated.
-Do not mix it with strong oxidants and strong acids.
-When storing, place it in a dry, cool place, and away from fire and flammable materials.

Although some properties and uses of 1-benzhydryl-4-(2-hydroxyethyl) piperazine dihydrochloride have been confirmed, it is still necessary to follow the standard operating procedures of laboratory and personal protection when using it, and follow relevant regulations and requirements.

Last Update：2024-04-10 22:29:15